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Protein Development and Production Unit

About the Protein Development and Production Unit

The Protein Development and Production Unit (PDPU), focuses on the production and development of new and existing cell lines to supply monoclonal antibodies and recombinant proteins for research, diagnostic and therapeutic use. Monoclonal antibodies for research use are marketed as IBGRL Research Products (IRP), while other reagents in our portfolio have been licensed for diagnostic use and bear the CE mark. IRP are used by both academic and commercial customers worldwide, in every continent except Antarctica.

Cell Culture Services   

 PDPU can undertake the following services on either a collaborative or commercial basis (this list is not exhaustive): 

  • Production of antibody and antigens from mouse, rat, human and insect cell lines
  • Protein purification, scale up and QC validation to customer specification including low endotoxin conditions
  • Antibody fragmentation and purification
  • CE marking of derived reagents
  • Development of customer cell lines, mycoplasma testing and optimisation including stability studies
  • New hybridoma and recombinant cell line generation, optimisation and stability studies
  • Provision of IBGRL cell lines under a license agreement

 

If you are interested in any of these cell culture services please complete a Service Request Form (FRM5846

If you would like to request a service that is not listed please contact us.   

Diagnostic Development

 We can undertake the following services either on a collaborative or commercial basis (this list is not exhaustive):

  • Antigen engineering
  • Antibody engineering including isotype switching & affinity maturation
  • Diagnostic assay development, validation & qualification (including CE marking)
  • Diagnostic platform development, validation & qualification

 

If you are interested in any of these diagnostic development services please complete a Service Request Form (FRM5849)

If you would like to request a service that is not listed please contact us.   

 

Please note: IBGRL does not currently undertake GMP manufacturing services but may support development of a GMP process.  Where responses indicate a request for GMP manufacturing, IBGRL will pass details onto the Cellular & Molecular Therapies and/or Tissue & Eye Services functions of NHSBT.