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Protein Development and Production Unit (PDPU)

Cell Culture Services   

 PDPU can undertake the following services on either a collaborative or commercial basis (this list is not exhaustive): 

  • Production of antibody and antigens from mouse, rat, human and insect cell lines
  • Protein purification, scale up and QC validation to customer specification including low endotoxin conditions
  • Antibody fragmentation and purification
  • CE marking of derived reagents
  • Development of customer cell lines, mycoplasma testing  and optimisation including stability studies
  • New hybridoma and recombinant cell line generation, optimisation and stability studies
  • Provision of  IBGRL cell lines under a license agreement

 

If you would like to request a service that is not listed please contact us.   

 

Diagnostic Development

 We can undertake the following services either on a collaborative or commercial basis (this list is not exhaustive):

  • Antigen engineering
  • Antibody engineering including isotype switching & affinity maturation
  • DNA plasmid engineering
  • Phage display library screening
  • Diagnostic assay development, validation & qualification (including CE marking)
  • Diagnostic platform development, validation & qualification

 

 If you would like to request a service that is not listed please contact us.   

 

Please note: IBGRL does not currently undertake GMP manufacturing services but may support development of a GMP process.  Where responses indicate a request for GMP manufacturing, IBGRL will pass details onto the Cellular & Molecular Therapies and/or Tissue & Eye Services functions of NHSBT.