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Recombinant Blood Group Proteins

Detection and identification of clinically significant blood group specific antibodies in patients requiring a blood transfusion can be difficult if antibodies to high frequency antigens are also present. Soluble recombinant (sr) proteins with blood group antigen activity can be used to inhibit haemagglutination by these ‘nuisance’ antibodies, allowing identification of underlying clinically significant antibodies. Sr proteins are pre-incubated with patient serum or plasma before the addition of the inhibited patient sample to panel red blood cells.

Knops Inhibition Reagent (KNIR) contains a mixture of two srCR1 proteins that inhibit red cell agglutination by anti-Knops/McCoy blood group specific antibodies in both gel and tube agglutination tests.

One vial is sufficient for up to 12 inhibition reactions.

This product is available to UK transfusion services and overseas customers.

Note: we ship this product by courier on dry ice. Store at -20°C

Product code
Product code
Antibody
Antibody
Specificity
Specificity
Class
Class
Light chain
Light chain
9497
Antibody
KNIR
Specificity
Knops Inhibition Reagent
Class
Recombinant protein
Light chain
N/A

Prices

All of our products are exclusive of VAT.  We ship our purified recombinant blood group protein products worldwide on dry ice by courier (Flight Logistics Group) and shipping fees will apply. Contact us if you require a quote, or have alternative courier arrangements. 

Quantity
(vials)
Quantity
(vials)
KNIR
GBP/vial
KNIR
GBP/vial
1 - 9
KNIR
GBP/vial
51.00
10 - 49
KNIR
GBP/vial
41.00
50 - 99
KNIR
GBP/vial
31.00
≥ 100
KNIR
GBP/vial
21.00

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