Molecular Diagnostics samples


IMPORTANT: Hospitals and reference centres wishing to refer for the first time must contact the Molecular Diagnostics laboratory before sending the sample to discuss the appropriateness of the proposed investigation.

Samples referred without the consent of the Molecular Diagnostics laboratory may not be investigated.

Please see the user guides and molecular diagnostics terms and conditions.

Fetal typing

Investigation
Investigation
Notes
Notes
Sample(s) required (minimum 0.5ml EDTA blood)
Sample(s) required (minimum 0.5ml EDTA blood)
Accompanying Form
Accompanying Form
Turnaround times
Turnaround times
Fetal Genotyping from Maternal Blood
Notes
Pregnancy must be at least 16 weeks for RhD/C/E/c Pregnancy must be at least 20 weeks for Kell typing.
Sample(s) required (minimum 0.5ml EDTA blood)
16ml EDTA blood per Rh test plus 3ml paternal blood if available (for RhD only)
Accompanying Form
FRM4674

Guidance

Turnaround times
Within 7 business days
Fetal Genotyping from Amniotic Fluid or Chorionic Villus
Notes
Sample(s) required (minimum 0.5ml EDTA blood)
5ml Amniotic fluid

For CV send pre-extracted DNA (min conc of 10ng/µl & min volume 60µl)

Accompanying Form
FRM4738

Guidance

Turnaround times
Within 10 business days
Fetal Sex Typing from Maternal Blood
Notes
Pregnancy must be at least 7 weeks.
Sample(s) required (minimum 0.5ml EDTA blood)
16ml EDTA blood
Accompanying Form
FRM4739

Guidance

Turnaround times
Within 5 business days

Blood Group Genotyping (patients and donors)

Please note that standard patient genotyping requests can be performed urgently, (<10 working days and within 48 hours), for an added premium of £125.00

Investigation
Investigation
Notes
Notes
Samples required (minimum 0.5ml EDTA blood)
Samples required (minimum 0.5ml EDTA blood)
Accompanying form
Accompanying form
Turnaround times
Turnaround times
Standard Genotyping
Notes
(RhD, C, c, E, e, K/k, Fya/b, Jka/b, M/N, S/s, U-, Uvar)
Samples required (minimum 0.5ml EDTA blood)
3ml EDTA blood
Accompanying form
FRM4738

Guidance

Turnaround times
Within 10 business days (or 48 hours for an added premium)
Extended Genotyping
Notes
RhD, C, c, E, e, V, VS, K/k, Kpa/b,Jsa/b, Fya/b, FyX, Jka/b, M/N, S/s, U-, Uvar , Lua/b, Dia/b, Coa/b, Doa/b, LWa/b, Sc as required
Samples required (minimum 0.5ml EDTA blood)
3ml EDTA blood
Accompanying form
FRM4738

Guidance

Turnaround times
Within 10 business days
Extended Genotyping (haemoglobinopathy array)
Notes
RhD, C, c, E, e, (including common RhD, C and e variants),V, VS, hrB, hrS , K/k, Kpa/b, Jsa/b,Doa/b, Fya/b, Jka/b, M/N, S/s, U-, Uvar
Samples required (minimum 0.5ml EDTA blood)
3ml EDTA blood
Accompanying form
FRM1597
Turnaround times
Within 12 weeks

Additional information