|IBGRL Red Cell Reference||
|Red Cell Reference||Molecular Diagnostics||User Guides||Sending Samples to Red Cell Reference|
The Red Cell Reference Department deals exclusively in complex and difficult red cell antigen/antibody problems. These problems take the form of:
Antibody identification may suggest potential clinical significance or act as a guide to the likely availability of compatible donors at a local level or via the National or International Rare Donor Panels.
Techniques used as an adjunct to serology in difficult cases include MAIEA, flow cytometry, molecular biology and immunoblotting.
Red cell serology services are provided to UK Blood Centres and to bona fide reference centres outside the UK. Centres wishing to refer for the first time must contact IBGRL to discuss the appropriateness of the proposed investigation.
Click here for further details on how to refer samples for investigation
Who We Are
The Red Cell
Reference Department of the IBGRL undertakes antibody and antigen
investigations of a ‘non-routine’ and complex nature.
Red cell antigen investigations may be carried out on all blood group systems where determination of phenotype is difficult or an uncommon polymorphism is suspected.
The laboratory has a unique collection of over 4000 rare typing sera and 2000 rare red cells. This enables the laboratory to solve the most complex serological problems.
One-half of referrals are from specialist centres in Europe, Japan, Australia and the USA. In collaboration with workers around the world, the laboratory continues to make important discoveries in the field of human blood groups. The laboratory also maintains the National and International Panels of Rare Donors.